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. Author manuscript; available in PMC: 2012 Jun 26.
Published in final edited form as: J Med Chem. 2011 May 19;54(12):4147–4159. doi: 10.1021/jm2002348

Figure 2. Expression of Nrf2-regulated genes in small intestine after treatment with chalcone derivatives.

Figure 2

Mice (n=4) were fed with vehicle (DCP-10% DMSO + 10% Cremophor + 80% phosphate buffered saline) or chalcone derivatives or sulforaphane (50 mg/kg body weight) by gavage, and the small intestines were harvested 24 h later. The expression of Nrf2-regulated genes GCLM and NQO1 was analyzed in the tissues by qRT-PCR as a surrogate marker of Nrf2 activity. β-actin was used for normalization. Data are representative of 3 independent experiments (P ≤ 0.05).