Skip to main content
. Author manuscript; available in PMC: 2012 Aug 1.
Published in final edited form as: Ther Drug Monit. 2011 Aug;33(4):433–438. doi: 10.1097/FTD.0b013e318224996e

Table 3.

Description of major bleeding events reported over 6-month data collection period

Description of
bleed		 INR at
time of
bleed		 Intervention Antidepressant at Time
of Bleed
ADP-WARF Cohort
Frank hematuria 3.4 Warfarin held Nortriptyline
Melena with low hemoglobin and hypotension 4.3 Admitted to hospital, warfarin held, and received 2 units of packed red blood cells Sertraline
Retroperitoneal hematoma following angiography 2.9 Prolonged time to hospital discharge, warfarin held, received 3 units of packed red blood cells Escitalopram
Gastrointestinal bleed with low hemoglobin 3.3 Admitted to hospital and underwent sigmoidoscopy and colonoscopy Sertraline
Low hemoglobin 2.2 Colonoscopy followed by tumor resection Fluoxetine
Fall resulting in hematoma with low hemoglobin 5.2 Admitted to hospital and warfarin held Paroxetine
WARF Cohort
Gastrointestinal bleeding with low hemoglobin 1.9 Admitted to hospital and received 3 units of packed red blood cells
Chest tube bleed 4.5 Emergency room visit and warfarin held
Hematoma 6.2 Received phytonadione 2.5 mg orally