Table 1. Modification of KEGG pathway metabolites induced by cadmium in Rhizobium alamii.
| KEGG pathway | Number of identified metabolitesCadmium concentration (mg.L−1) | |
| 0 | 2 | |
| Glycolysis/Gluconeogenesis | 0 | 7 |
| Citrate cycle (TCA cycle) | 3 | 0 |
| Pentose phosphate pathway | 0 | 6 |
| Pentose and glucuronate interconversions | 1 | 4 |
| Fructose, mannose, inositol and galactose metabolism | 12 | 44 |
| Purine, pyrimidine metabolism | 30 | 26 |
| Lysine biosynthesis | 10 | 2 |
| Glutathione metabolism | 1 | 1 |
| Starch and sucrose metabolism | 6 | 21 |
| Nucleotide sugars metabolism | 0 | 2 |
| Lipopolysaccharide biosynthesis | 0 | 1 |
| Peptidoglycan biosynthesis | 1 | 2 |
| Inositol phosphate metabolism | 0 | 7 |
| ABC transporters | 13 | 20 |
| Two-component systems | 0 | 2 |
| Phosphotransferase system | 9 | 17 |
Rhizobium alamii cells were grown up to a late exponential phase, with 2 mg.L−1 of cadmium, as compared to the absence of cadmium. The potential metabolites identified were matched in KEGG pathway using MassTRIX (http://masstrix.org).