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. 2011 Nov 9;6(11):e27461. doi: 10.1371/journal.pone.0027461

Figure 4. Effect of lithium administration on Ptau AT270 inclusions in the dentate gyrus.

Figure 4

MPS IIIB (−/−) or control (+/−) mice were provided with LiCl in their chow, 3 g/kg, or fed regular chow, as indicated. Each group consisted of 8 male mice. Treatment was begun while the mice were nursing and ended with euthanasia at 3 months. The number of dentate gyrus inclusions staining with antibody AT270 was determined by counting 12 fields that include the dentate gyrus of the hippocampus. The bars represent the mean and standard deviation of the number of AT270 positive inclusions.