Table 2.
MicroRNAs up- and down-regulated by wt Nras
| miR Upregulated by Nras in SV40 cells
| |||
|---|---|---|---|
| Name | FC (average) | STDEV | Predicted Targets |
| let_7b | 2.66 | 0.60 | Adamts5, Rab9, Pappa, Col6a2, Pcdhb9, Nid2, Rras, Stat3 |
| let_7a | 2.50 | 0.61 | Col6a2 |
| miR_125b | 2.37 | 0.32 | Igf2 |
| miR_99b | 2.23 | 1.19 | None |
| miR_29a | 2.23 | 0.08 | Tgfb1i4, Col6a2, Nid2, Ctsk, Cav2 |
| miR_27a | 2.03 | 0.66 | Rabl4, Idb4, Gstm1 |
| miR_16 | 1.96 | 0.37 | Rabl4, Bcl2l2, Adamts5, Capn6 |
| let_7d | 1.88 | 0.49 | Adamts5, Pappa, Col6a2 |
| miR_23b | 1.75 | 0.19 | Fnta, Col6a1, Capn6 |
| let_7f | 1.75 | 0.43 | Pappa, Col6a2 |
| miR_23a | 1.65 | 0.26 | Fnta, Col6a1, Capn6 |
|
| |||
| miR Downregulated by Nras in SV40 cells
| |||
| Name | FC (average) | STDEV | Predicted Targets |
| miR_26a | 0.64 | 0.17 | Atm |
| miR_26b | 0.54 | 0.21 | None |
| miR_34a | 0.44 | 0.14 | Gmn |
| miR_449 | 0.41 | 0.17 | Gmn, Hoxd8 |
| miR_298 | 0.41 | 0.24 | None |
| miR_33 | 0.39 | 0.11 | Gmn |
| miR_499 | 0.37 | 0.10 | Aurkb, Dnmt1 |
| miR_183 | 0.37 | 0.17 | None |
| miR_140 | 0.37 | 0.04 | None |
| miR_122a | 0.37 | 0.12 | None |
| miR_421 | 0.36 | 0.09 | Dnmt1 |