Table 4.
Fluorophore | Time Interval | Performance | Pros and Cons | |
---|---|---|---|---|
MB | 0 – 10 min | ++ | ||
10 – 90 min | ++ | Multiple injections without high background | ||
≥ 90 min | ++ | |||
ICG | 0 – 10 min | ++ | Multiple injections without high background | |
10 – 90 min | − | Interference from ICG accumulation in liver and clearance into bile, leading to high background | ||
≥ 90 min | + | Artery can be visualized although bile ducts are still very bright | ||
ZW800-1 | 0 – 10 min | ++ | ||
10 – 90 min | ++ | Multiple injections without high background | ||
≥ 90 min | ++ |
++: High contrast arterial imaging (mean CBR of artery > both mean CBR of liver and mean CBR of CBD)
+ : Low contrast arterial imaging (mean CBR of artery < either mean CBR of liver or mean CBR of CBD)
− : Poor contrast arterial imaging (mean CBR of artery < both mean CBR of liver and mean CBR of CBD)