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. 2002 Jan 7;195(1):85–98. doi: 10.1084/jem.20011578

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Copyright © 2002, The Rockefeller University Press

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Figure 1. — Recombination substrate (not to scale). The upstream cassette is comprised between M (Mlu1) and S (Sal1). The downstream cassette is comprised between Sp (Spe1) and Sc (Sac2) or N (Not1). The authentic RSS is shown as a triangle (a). Fortuitous RSSs are represented as incomplete triangles: b, fortuitous RSS observed in proto-oncogene translocation breakpoints, c, other potential fortuitous RSS in proto-oncogene flanking sequence, d, other fortuitous RSS in core plasmid sequence. Pathways 1–3: V(D)J recombination; Pathway 4: BR. Horizontal arrows indicate the location of the PCR screen primers.