Table 3. Sensitivity, specificity, positive and negative predictive values for predicting HBVa reactivation within one year according to the different cutoff values of serum HBV DNA level.
Cutoff value (IU/mL) | Sensitivity (%) | Specificity (%) | PPV a (%) | NPV a (%) |
20 | 97.6 | 32.9 | 26.3 | 98.2 |
50 | 97.6 | 38.9 | 28.2 | 98.5 |
100 | 92.7 | 59.3 | 35.8 | 97.1 |
200 | 85.4 | 69.5 | 40.7 | 95.1 |
500 | 61.0 | 81.4 | 44.6 | 89.5 |
1,000 | 41.5 | 93.4 | 60.7 | 86.7 |
a HBV: HepatitisB virus, PPV: Positive predictive value, NPV: Negative predictive value