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. 2011 Sep 23;26(12):3249–3263. doi: 10.1093/humrep/der317

Table III.

Effects of oxamate on motility and endogenous ATP levels of capacitated human spermatozoa.

Sperm parameter EC50 (mM)a Maximal inhibition (%)b
Motility 2.9 ± 0.7 31 ± 1
Progressive motility 1.8 ± 0.4 94 ± 1
VCL 1.0 ± 0.3 42 ± 3
Hyperactive motility 1.0 ± 0.3 95 ± 2
ATP 0.5 ± 0.1 82 ± 3

Numbers are given as mean values ± SEM of three separate experiments.

aEC50 values (mM).

bMaximum inhibition (%) of sperm motility and ATP production by a titration of oxamate.