Table 4.
Risk of pancreatic cancer in relation to intake of nutritional factors in a population-based case-control study of pancreatic cancer in Minnesota, 1994-1998
| Quartile |
P trenda | ||||
|---|---|---|---|---|---|
| Nutrient/food | First | Second | Third | Fourth | |
| Energy (kcal/day) | |||||
| Median | 1,291 | 1,779 | 2,160 | 2,818 | |
| Cases/controls | 48/138 | 47/139 | 43/139 | 48/138 | |
| OR1 (95% CI)b | 1.00 | 0.93 (0.58, 1.51) | 0.81 (0.49, 1.33) | 0.89 (0.54, 1.46) | 0.59 |
| OR2 (95% CI)c | 1.00 | 1.16 (0.65, 2.06) | 1.26 (0.64, 2.52) | 1.89 (0.72, 5.10) | 0.23 |
| Saturated fat (gram/day) | |||||
| Median | 12.3 | 18.3 | 24.8 | 36.6 | |
| Cases/controls | 38/138 | 50/139 | 40/139 | 58/138 | |
| OR1 (95% CI)b | 1.00 | 1.27 (0.77, 2.10) | 0.99 (0.59, 1.69) | 1.27 (0.77, 2.11) | 0.51 |
| OR2 (95% CI)c | 1.00 | 1.67 (0.93, 3.03) | 1.56 (0.80, 3.09) | 2.47 (1.07, 5.86) | 0.061 |
| Monounsaturated fat (gram/day) | |||||
| Median | 13.8 | 21.0 | 28.5 | 40.7 | |
| Cases/controls | 45/138 | 41/139 | 43/139 | 57/138 | |
| OR1 (95% CI)b | 1.00 | 0.81 (0.49, 1.34) | 0.89 (0.54, 1.46) | 1.05 (0.65, 1.72) | 0.65 |
| OR2 (95% CI)c | 1.00 | 0.92 (0.51, 1.65) | 1.27 (0.66, 2.44) | 2.00 (0.87, 4.68) | 0.073 |
| Polyunsaturated fat (gram/day) | |||||
| Median | 6.7 | 10.0 | 13.4 | 19.4 | |
| Cases/controls | 39/138 | 50/139 | 42/139 | 55/138 | |
| OR1 (95% CI)b | 1.00 | 1.24 (0.75, 2.05) | 1.00 (0.59, 1.68) | 1.31 (0.80, 2.16) | 0.41 |
| OR2 (95% CI)c | 1.00 | 1.55 (0.88, 2.76) | 1.58 (0.83, 3.03) | 2.56 (1.19, 5.58) | 0.024 |
| Total fat (gram/day) | |||||
| Median | 37.5 | 55.0 | 73.0 | 102.0 | |
| Cases/controls | 45/138 | 40/139 | 44/139 | 57/138 | |
| OR1 (95% CI)b | 1.00 | 0.78 (0.47, 1.29) | 0.90 (0.55, 1.48) | 1.04 (0.64, 1.70) | 0.64 |
| OR2 (95% CI)c | 1.00 | 1.02 (0.57, 1.84) | 1.42 (0.74, 2.78) | 2.16 (0.91, 5.27) | 0.059 |
| Fiber (gram/day) | |||||
| Median | 14.0 | 20.0 | 25.0 | 35.0 | |
| Cases/controls | 64/137 | 45/140 | 40/139 | 37/138 | |
| OR1 (95% CI)b | 1.00 | 0.69 (0.43, 1.10) | 0.54 (0.33, 0.87) | 0.58 (0.35, 0.94) | 0.021 |
| OR2 (95% CI)c | 1.00 | 0.71 (0.41, 1.20) | 0.49 (0.26, 0.94) | 0.52 (0.21, 1.30) | 0.11 |
| Fruit (serving/week) | |||||
| Median | 8.0 | 14.5 | 21.5 | 33.5 | |
| Cases/controls | 62/139 | 38/139 | 33/138 | 53/138 | |
| OR1 (95% CI)b | 1.00 | 0.71 (0.43, 1.16) | 0.56 (0.33, 0.94) | 0.91 (0.57, 1.47) | 0.83 |
| OR2 (95% CI)c | 1.00 | 0.86 (0.50, 1.47) | 0.68 (0.37, 1.23) | 1.30 (0.67, 2.52) | 0.47 |
| Vegetable (serving/week) | |||||
| Median | 9.0 | 15.0 | 23.0 | 36.3 | |
| Cases/controls | 63/136 | 55/136 | 32/140 | 36/142 | |
| OR1 (95% CI)b | 1.00 | 0.93 (0.59, 1.46) | 0.49 (0.29, 0.82) | 0.64 (0.38, 1.05) | 0.026 |
| OR2 (95% CI)c | 1.00 | 0.94 (0.57, 1.55) | 0.57 (0.31, 1.04) | 0.84 (0.41, 1.72) | 0.47 |
a
Linear trend across quartiles.
b
Adjusted for age, sex, race, education, cigarette smoking, and alcohol intake.
c
Additionally adjusted for physical activity and intakes of all other dietary factors; saturated fat, monounsaturated fat, polyunsaturated fat, and total fat were not adjusted for each other.