Skip to main content
. Author manuscript; available in PMC: 2011 Nov 10.
Published in final edited form as: Exp Eye Res. 2007 Aug 29;85(6):799–805. doi: 10.1016/j.exer.2007.08.015

Table 2.

Scoring individual characteristics of ocular disease severity (see methods) in the murine scarification model of P. aeruginosa keratitis after inoculation with 5 μl of cell culture medium containing ~1 × 106 cfu strain PA103ΔexoUexoT::Tc (PA103ΔUT) complemented with pUCP18, pUCPexoU, or pUCPexoUD344A.

Total Disease Scores at 48 h
[= Area + Density + Epithelial Quality]
Each Scored From 0 to 4, Possible Maximum = 12
PA103ΔUT + pUCP18 PA103ΔUT + pUCPexoU* PA103ΔUT + pUCPexoUD344A
Mouse 1 8
[4+2+2]		 10
[4+3+3]		 9
[4+3+2]
Mouse 2 8
[4+2+2]		 10
[4+4+2]		 8
[4+3+1]
Mouse 3 9
[4+3+2]		 10
[4+4+2]		 7
[3+3+1]
Mouse 4 8
[4+2+2]		 11
[4+4+3]		 7
[3+3+1 ]
*

Disease involving pUCPexoU was of increased overall severity compared to the phospholipase catalytic mutant (p = 0.017, Mann-Whitney Test) which was not different from control (p = 0.350, Mann-Whitney Test).