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. 2004 Jan;11(1):60–69. doi: 10.1101/lm.70004

Figure 4.

Figure 4

Nicotine increases the amplitude of evoked EPSCs recorded from VTA DA neurons. Example traces (upper) show that bath-applied nicotine (1 μM) increases the amplitude of eEPSCs, and the average (five of 11; six showed no change) shows the long-lasting effect of the amplitude increase (lower). A low concentration of EGTA (0.4 μM) was used in the patch pipette to enhance the long-lasting increase in amplitude. The recordings were at room temperature at a holding potential of –65 mV, and a weak simulation strength was used. The scale bars represent 100 pA and 10 msec.