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. 2011 Nov 10;7(11):e1002362. doi: 10.1371/journal.pgen.1002362

Figure 1. G1 Cyclin/CDK expression induces mitotic events in body-wall muscle cells.

Figure 1

(A) Control animal expressing the GFP::H2B fusion protein in body-wall muscle. (B) Animals that express CYE-1, CDK-2AF and GFP::H2B together from the myo-3 promoter show chromosome condensation (arrow) and nuclear division (arrowhead) in differentiated body-wall muscle. (C) Quantification of mitotic events for each Cyclin/CDK combination at the L3 stage. Each dot represents the number of mitotic muscle nuclei (with condensed DNA, metaphase or anaphase figures or nuclear division) in a single animal. In each animal, 58 muscle nuclei anterior of the prospective vulva were counted, to exclude muscle cells formed during post-embryonic development in the Mesoblast lineage. The highest mitotic index was 12% (7/58) in the strain with both Cyclin/CDKs. Error bars represent S.E.M.