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. 2011 Nov 10;6(11):e27602. doi: 10.1371/journal.pone.0027602

Table 5. Performance of each system for predicting siRNA efficacy (i.e., ≥70% inhibition of the target mRNA).

Predictive system	Acc (%)	Sn (%)	Sp (%)	MCC
siPRED	75.66	83.10	67.96	0.517
i-Score	55.61	15.49	97.09	0.216
s-Biopredsi	67.30	55.40	79.61	0.360
ThermoComposition21	70.41	72.77	67.96	0.407
DSIR	70.64	74.18	66.99	0.412