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. 2011 Nov 10;7(11):e1002264. doi: 10.1371/journal.pcbi.1002264

Figure 7. Signaling time depends on the number of initiation events.

Figure 7

Inline graphic can increase or decrease as a function of Inline graphic depending on the value of Inline graphic. Here Inline graphic. (A) Inline graphic vs. CV of Inline graphic for Inline graphic varying from Inline graphic (red) to Inline graphic (green) to Inline graphic (blue) using the Bernoulli delay distribution Inline graphic in Example with Inline graphic. Note the transition that occurs at Inline graphic. (B) Equivalent to (A), but plotting CV of the signaling time instead of conditional expectation. (C) and (D) Contour plots corresponding to (A) and (B), respectively. Notice that for fixed Inline graphic, signaling time CV can change non-monotonically with Inline graphic. For instance, at Inline graphic, signaling time CV starts low (red), increases to Inline graphic (green) and then decreases thereafter. Plots were obtained through stochastic simulation with Inline graphic trials.