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Leukocyte rolling (a) and firm adhesion (b) in hepatic postsinusoidal venules 6 h after treatment with a combination of LPS (10 μg) and Gal (18 mg) and monoclonal antibodies against P-selectin (RB40.34, 40 μg; anti-P), E-selectin (10E9.6, 40 μg; anti-E), or L-selectin (Mel-14, 40 μg; anti-L) or PBS. Control animals received PBS. Data represent means ± SEM. Asterisks indicate significant differences versus challenge with LPS-Gal plus PBS (P < 0.05).
