TABLE 1.
Challenge | No. of:
|
||
---|---|---|---|
MNL | PMNL | Total cells | |
PBS (control) | 3.5 ± 0.5 | 1.9 ± 0.4 | 5.4 ± 0.8 |
LPS-Gal + PBS | 3.1 ± 0.4 | 1.5 ± 0.3 | 4.5 ± 0.5 |
Anti-P + LPS-Gal | 3.7 ± 0.3 | 1.7 ± 0.5 | 5.4 ± 0.7 |
Anti-E + LPS-Gal | 4.2 ± 0.7 | 2.1 ± 0.5 | 6.3 ± 0.8 |
Anti-L + LPS-Gal | 1.4 ± 0.3* | 0.9 ± 0.4* | 2.3 ± 0.5* |
Leukocytes were counted in a hematocytometer and were defined as MNL or PMNL. Animals were challenged with PBS (control), LPS-Gal plus PBS, or LPS-Gal plus antibodies against P-, E-, or L-selectin (anti-P, -E, and -L, respectively). Data are given as means ± SEM and represent 106 cells/milliliter. Asterisks indicate significant differences versus challenge with LPS-Gal plus PBS.