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. Author manuscript; available in PMC: 2012 Dec 1.
Published in final edited form as: Traffic. 2011 Oct 9;12(12):1911–1922. doi: 10.1111/j.1600-0854.2011.01280.x

Figure 5. Nocodazole destabilizes the Rab5a cycle on macropinosomes.

Figure 5

(A) Rab5a activation on a macropinosome of a cell in nocodazole; top, phase-contrast; bottom, EO, phase-contrast with overlay showing inactive CFP-Rab5a (red) and active CFP-Rab5a (green), with the threshold for CFP-Rab5a activation set at EAVG = 10%. Rab5a activity fluctuates on the macropinosome. Scale bar = 5 μm. (B–E) Individual traces from macropinosomes in nocodazole-treated cells.