Table 1.
Intramuscular Vaccine Administration Titers
| Serum C5a-IgG | 4 weeks (n) | 8 weeks (n) | 11 weeks (n) | 40 weeks (n) |
|---|---|---|---|---|
| 75:25 10ug | 1000 (27) | 100000 (27) | 100000 (27) | 1000 (11) |
| 75:25 30ug | 100000 (28) | 100000 (26) | 100000 (25) | 100000 (4) |
| 50:50 30ug | 100000 (28) | 100000 (27) | 100000 (27) | 100000 (6) |
| Serum C5a-IgA | ||||
| 75:25 10ug | 100000 (27) | 100000 (27) | 100000 (27) | 0 (11) |
| 75:25 30ug | 0 (28) | 10000 (26) | 100000 (25) | 10000 (4) |
| 50:50 30ug | 0 (28) | 0 (27) | 100000 (27) | 10000 (6) |
| Vaginal C5-IgG | ||||
| 75:25 10ug | 100000 (27) | 100000 (27) | 100000 (27) | 1000 (11) |
| 75:25 30ug | 10000 (28) | 10000 (26) | 100 (25) | 100000 (4) |
| 50:50 30ug | 100000 (28) | 10000 (27) | 10000 (27) | 100000 (6) |
| Vaginal C5a-IgA | ||||
| 75:25 10ug | 100000 (27) | 100000 (27) | 0 (27) | 0 (11) |
| 75:25 30ug | 10000 (28) | 100000 (26) | 100 (25) | 100000 (4) |
| 50:50 30ug | 1000 (28) | 0 (27) | 10000 (27) | 10000 (6) |
Titers are shown as 1:Y (Y represents the dilution). A Student’s t-test was used to determine the significant titer. The largest dilution tested that was significantly different from mice receiving 75:25 0ug is the reported titer.