TABLE 3.
Sensitivity and specificity of the Determine Rapid Syphilis TP assay by reader type and HIV status using the TPHA as the reference standarda
| Reader | HIV positive (n = 198)
|
HIV negative (n = 127)
|
||
|---|---|---|---|---|
| % Sensitivity (95% CIb) | % Specificity (95% CI) | % Sensitivity (95% CI) | % Specificity (95% CI) | |
| Laboratorian 1 | 98.5 (93.7-99.6) | 95.5 (86.3-98.5) | 94.4 (83.3-98.2) | 100 (88.6-100%) |
| Laboratorian 2 | 99.2 (94.2-99.8) | 92.5 (82.5-96.8) | 96.3 (85.2-99.0) | 97.3 (88.8-99.3) |
| Nurse | 97.7 (92.4-99.2) | 92.5 (82.2-98.9) | 94.4 (83.1-98.1) | 98.6 (89.8-99.8) |
a
Three hundred twenty-five samples were tested, excluding samples without clinical data (n = 227) and those TPHA indeterminate (n = 15).
b
CI, confidence interval.