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. 2011 Nov;189(3):1061–1068. doi: 10.1534/genetics.111.131813

Figure 3.

Figure 3

Results are shown for scenarios where multiple (i.e., 5) disease susceptibility variants (DSVs) are present at the disease locus. The relationship between the GRR and disease variant frequency is shown in the first column. In the top panel, the GRR is a decreasing function of variant frequency, while in the bottom panel, the GRR is the same (i.e., 2) regardless of variant frequency. The third column presents results when 10 additional random variants (i.e., not disease variants) are also present.