Table 1. The effective number of variants, keff|2, at a rare variant position in two related individuals that each carry a variant, as defined in Equation 1.
keff|2 | |||
---|---|---|---|
Relationship | φ | f = 0.001 | f = 0.01 |
Identical twins | 1.00 | 1.00 | |
Parent–child | 1.11 | 1.17 | |
Sibs | 1.11 | 1.17 | |
Half-sibs | 1.22 | 1.34 | |
Uncle–nephew | 1.22 | 1.34 | |
First cousins | 1.33 | 1.50 | |
First cousins-1 (once removed) | 1.44 | 1.64 | |
Second cousins | 1.55 | 1.76 | |
Unrelateds | 0 | 2.00 | 2.00 |
φ is the kinship coefficient. Results for two values of the frequency parameter f, 0.001 and 0.01, are shown.