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. 2011 Nov;189(3):861–870. doi: 10.1534/genetics.111.131482

Figure 1 .

Figure 1 

Identification of a deletion on the X chromosome causing dilated cardiomyopathy. (A) Schematic of the Df(1)Exel6245 deletion containing 14 genes on the X chromosome. Df(1)f08066-f07791 represents the flp-mediated recombination deletion made with transposons f08066 and f07791, covering 3 genes including RpS15Aa. (B) Representative M-mode recordings of Drosophila cardiac function reflecting the change in cardiac chamber dimension over time. Control w1118 and representative dilated images of Df(1)Exel6245/FM7c and Df(1)f08066-f07791/FM7c are shown. End-diastolic and end-systolic positions are delineated with vertical, white lines. (C) Summary of cardiac function for w1118, Df(1)Exel6245/FM7c, and Df(1)f08066-f07791/FM7c. Mean ±SEM for each group, n = 16–25 per group shown in parentheses. *P < 0.01 compared to w1118, one-way ANOVA.