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. 2011 Aug 8;589(Pt 19):4671–4679. doi: 10.1113/jphysiol.2011.216218

Table 2.

Dose–response curve parameters for skin blood flow (SkBF) during stepwise infusion of the ET-B receptor antagonist (BQ-788) and the ET-A receptor antagonist (BQ-123) in women with (PCOS) and without (Control) polycystic ovary syndrome

ET-A ET-B


PCOS Control PCOS Control
logED50 (nm) 2.53 ± 0.09 2.49 ± 0.09 2.56 ± 0.09 2.41 ± 0.12
ED50 (nm) 342.3 312.1 358.8 258.8
95% CI 221.6–528.8 204.9–475.5 141.0–473.8 233.5–551.4
Slope (%max SkBF/log[ET]) 4.96 ± 4.77 4.74 ± 5.01 4.69 ± 3.85 4.03 ± 3.85

Data are presented as mean (SD).