Table 1.

Body and organ weights of control and dexamethasone (DEX)-treated female and male wild type (WT) and MuRF1 null (KO) mice

Females	WT Con (n = 9)	WT DEX (n = 8)	KO Con (n = 7)	KO DEX (n = 8)
Starting BW (g)	22.3 ± 2.8	20.1 ± 1.3	25.4 ± 0.5†	25.1 ± 1.6
Final BW (g)	22.2 ± 2.4	18.1 ± 1.6*	26.4 ± 2.1	23.9 ± 2.7*
Heart (mg)	119.7 ± 16.9	105.6 ± 15¶	146.1 ± 7.7†	143.5 ± 8.2
Spleen (mg)	85.9 ± 10.4	37.3 ± 6.5¶	86.3 ± 6.0	40.4 ± 7.1¶

Males	WT Con (n = 9)	WT DEX (n = 10)	KO Con (n = 8)	KO DEX (n = 8)
Starting BW (g)	29.3 ± 2.5	29.4 ± 1.5	32.3 ± 2.6†	32.5 ± 2.3
Final BW (g)	29.0 ± 0.004	27.0 ± 1.7*	33.6 ± 2.2	30.4 ± 3.0*
Heart (mg)	143.4 ± 18.8	138.9 ± 15.2	178.1 ± 11.8†	169.8 ± 15.8¶
Spleen (mg)	80.0 ± 12.0	55.0 ± 7.7¶	76.4 ± 8.3	44.3 ± 5.2¶

Female and male WT and MuRF1 KO mice were treated with DEX for 14 days. The average (mean ± SD) starting body weight (BW), final body weight, heart mass and spleen mass of control (Con) and DEX-treated mice was calculated upon completion of the experiment.

^*Statistical difference between starting and ending BW (P < 0.05)

^†statistical difference between control WT and KO mice

^¶statistical difference control and DEX treatment within each group (P < 0.05).