Table 1.
Effects of VitD deprivation in utero and into young adulthood on serum 25-hydroxyvitamin D and Ca2+, body mass, mean arterial pressure (MAP) and heart rate in 7- to 8-week-old rats
Males | Females | |||||
---|---|---|---|---|---|---|
Control fed | Vit D deplete | P | Control fed | Vit D deplete | P | |
Serum 25OH-D (nmol l-1) | 120 ± 7 | 13 ± 1 | <0.001 | 138 ± 14 | 10 ± 1 | <0.001 |
Serum Ca2+ (mmol l−1) | 2.29 ± 0.06 | 2.19 ± 0.10 | 0.7 | 2.36 ± 0.05 | 2.29 ± 0.07 | 0.3 |
MAP (mmHg) | 104 ± 1 | 115 ± 2 | 0.001 | 102 ± 2 | 122 ± 2 | <0.001 |
Heart rate (beats min−1) | 378 ± 6 | 418 ± 8 | 0.002 | 394 ± 5 | 415 ± 5 | 0.02 |
For males, n = 13 for control fed and n = 12 for VitD deplete; for females, n = 8 and 13 for control fed and VitD deplete, respectively. Values are given as means ± SEM. Vit D, vitamin D; MAP, mean arterial pressure; 25OH-D, 25-hydroxyvitamin D.