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Effects of aldosterone blockade in uninephrectomized mice during chronic ANG II infusion. A: daily, 24-h blood pressures measured by radiotelemetry during chronic ANG II infusion in uninephrectomized WT mice implanted with vehicle (Control) or spironolactone (Spiro) pellets to block actions of aldosterone, n = 8. B: urinary albumin excretion measured by ELISA in the Control and Spiro groups following 4 wk of ANG II infusion.
