Fig. 1.
Bladder morphology. Hematoxylin and eosin staining of fixed cryosectioned (6 μm) mouse bladder shows the trilaminar structural elements, which include urothelium (U), lamina propria (LP; double-headed arrow), and detrusor smooth muscle. Blood vessels (BV) are indicated within the LP. Inset i, expanded region of U which is compressed between folds and exhibits thickening and multiple cell layers; inset ii, expanded region of U which is much thinner and exhibits cell compression. Arrowheads point to umbrella cell nuclei, and dotted line indicates U/LP boundary. Scale bar = 100 μm.