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Changes in plasma C-natriuretic peptide (CNP; A), urinary CNP excretion (B), urinary-to-plasma CNP ratio (C), and proteinuria (D) between 2-, 11-, and 20-mo-old Fischer rats. Values are means ± SE; n = 10 for all age groups. *P < 0.05 vs. 2 mo. †P < 0.05 vs. 11 mo.
