Table 1.

Summary of body weight, renal characteristics, and blood pressure in aging Fischer rats

	2 mo	11 mo	20 mo
BW, g	211 ± 2	465 ± 5*	445 ± 7*†
TKW, mg	1,614 ± 33	2,763 ± 73*	2,750 ± 54*
TKW:BW, mg/g	7.67 ± 0.19	5.94 ± 0.15*	6.18 ± 0.13*
Plasma Cr, mg/dl	0.20 ± 0.00	0.39 ± 0.03*	0.36 ± 0.02*
GFR, ml·min−1·kg−1	3.52 ± 0.29	2.61 ± 0.43	2.83 ± 0.30
MAP, mmHg	90 ± 1	91 ± 2	100 ± 3*†

Values are means ± SE; n = 10 for all age groups.

BW, body weight; TKW, total kidney weight; Cr, creatinine; GFR, glomerular filtration rate; MAP, mean arterial pressure.

^*P < 0.05 vs. 2 mo.

^†P < 0.05 vs. 11 mo.