Fig. 6.
Comparison of RUSMC ScTx-sensitive Kv current with currents from HEK cells stably transfected with Kv2.1 and Kv2.2 channels. A: typical family of ScTx-sensitive difference currents obtained by digitally subtracting the current in the presence of ScTx from the control currents. B: mean activation data obtained from the ScTx-sensitive difference currents from 12 RUSMC. C and D: typical family of Kv2.1 currents and the associated activation curve, respectively. E and F: typical Kv2.2 currents and the summary activation curve, respectively. The solid lines in B, D, and F show the Boltzmann fits of the mean data ± SE. Gmax, maximal conductance; V1/2, voltage at half-maximal activation.