. 2011 Aug 24;301(5):R1440–R1452. doi: 10.1152/ajpregu.00298.2011

Table 3.

Minimum biomarker proteins required to define the skeletal muscle proteome during hibernation using Random Forests clustering

Gene Symbol	Protein name	Spot No.
All states
DUSP3	Dual specificity phosphatase 3	2051⁽¹⁾
PDK4	Pyruvate dehydrogenase kinase isozyme 4	1244⁽²⁾
HSPB1	Heat shock protein β1	1863⁽³⁾
HSPB6	Heat shock protein β6	2073⁽⁴⁾
APOA1	Apolipoprotein A1	1846⁽⁵⁾
TPT1	Translationally controlled tumor protein 1	1940⁽⁶⁾
HBB	β-hemoglobin	2316⁽⁷⁾, 2310⁽⁹⁾, 2318⁽¹⁰⁾
IMMT	Mitofilin	657⁽⁸⁾
Winter states only
HSPB1	Heat shock protein β1	1863⁽¹⁾, 1878⁽⁷⁾
DUSP3	Dual specificity phosphatase 3	2051⁽²⁾
HSPB6	Heat shock protein β6	2073⁽³⁾
ANKRD2	Ankyrin repeat domain 2	1374⁽⁴⁾, 1337⁽¹²⁾
NME2	Nucleoside diphosphate kinase B	2141⁽⁵⁾
HBB	β-hemoglobin	2316⁽⁶⁾, 2310⁽⁸⁾, 2318⁽¹⁰⁾
UBA1	Ubiquitin-activating enzyme E1	310⁽⁹⁾
IMMT	Mitofilin	657⁽¹¹⁾

Known proteins required for equivalent or improved clustering compared with all matched spots are presented. Rankings of spot importance to the Random Forests clustering are noted in parentheses.