Fig. 3.

Sepsis fragments sleep of rats. The number of transitions from one behavioral state to another were determined hourly from control rats (SHAM, ●) and septic rats (CLP, ■) during presurgical baseline recordings (open symbols) and during postsurgical recording days (solid symbols). Data are presented as means ± SE. Statistical evaluations were performed on consecutive 6-h time blocks. Statistically significant differences between baseline and postsurgical values across time blocks are indicated as *P ≤ 0.05. The black bars on the x-axis indicate the dark portion of the light-dark cycle.