Fig. 2.

Ameliorative effects of GSNO are sustained. A: schematic showing experimental protocol. B and C: airway resistance in alum control or OVA mice was measured by flexiVent 2 min to 4 h after nose-only inhalation of aerosolized PBS or 10 mM GSNO. Data in C are area under the curve (AUC) of Fig. 1B. D: total S-nitrosothiols in BAL from PBS- or GSNO-treated mice were quantified by mercury-coupled photolysis chemiluminescence. Data in B and C are means ± SE (n = 8–11 per group), *P < 0.001. Data in D are means + SE (n = 3–4 per group).