Fig. 7.

Peripheral delivery of OVT distorts feeding circadian rhythm to promote obesity. Chow-fed adult male C57BL/6 mice with matched body weight were divided into two groups to receive ip injection of OVT vs. vehicle at the beginning of daytime on a daily basis for 1 wk. Data shown are accumulated weekly daytime (A) vs. nighttime (B) caloric intake and diurnal ratio of feeding (C) during the 1-wk treatment and body weight (D) following the completion of the 1-wk treatment. *P < 0.05; n = 5–7/group. Error bars represent means ± SE.