Table 1. mRNA expression profile of transporters and enzymes important for simple carbohydrate catabolism in HepG2 cells and human tissues using real-time PCR.
| Gene | |||||
| GLUT 2 | GLUT 5 | HK 2 | GCK | KHK | |
| Tissue | % of human liver mRNA abundance | ||||
| Liver | 100 | 100 | 100 | 100 | 100 |
| HepG2 | 67 | 132 | 14262 | ND | 175 |
| Dorsal Root Ganglion | ≤1 | 1759 | 201 | ≤1 | 10 |
| Spleen | ND | 387 | 272 | ≤1 | ≤1 |
| Stomach | ≤1 | 360 | 484 | 2 | 4 |
| Bone Marrow | ND | 6824 | 1287 | ND | ≤1 |
| Heart | ≤1 | 938 | 497 | ≤1 | 2 |
| Kidney | 29 | 14374 | 85 | ≤11 | 396 |
| Lung | ND | 209 | 984 | ND | 4 |
| Placenta | ND | 776 | 994 | ND | ≤1 |
| Skeletal Muscle | ND | 11259 | 2661 | ≤1 | 2 |
| Spinal Cord | ≤1 | 10960 | 1188 | 9 | 9 |
| Testis | ≤1 | 64189 | 10151 | 5 | 17 |
| Uterus | ND | 331 | 141 | ≤1 | 4 |
| Colon | ND | 2069 | 6975 | ≤1 | 14 |
| Pancreas | ≤1 | 22.1 | 28 | 14 | 2 |
| Small Intestine | 21 | 26820 | 110 | ≤1 | 97 |
| Fetal Liver | 33 | 191 | 182 | ND | 21 |
| Fetal Brain | ≤1 | 1467 | 478 | 4 | 17 |
| Adrenal Gland | ≤1 | 493 | 199 | 2 | 4 |
| Brain | ≤1 | 1494 | 311 | 9 | 16 |
| Cerebellum | ND | 75 | 1077 | ND | 5 |
| Prostate | ≤1 | 6702 | 807 | ≤1 | 2 |
| Salivary Gland | ND | 112 | 225 | ≤1 | 2 |
| Thymus | ≤1 | 661 | 477 | 2 | ≤1 |
| Thyroid | ≤1 | 197 | 837 | 20 | 2 |
| Trachea | ≤1 | 209 | 592 | ND | 2 |
GLUT 2 (SLC2A2), solute carrier family 2 member 2; GLUT 5 (SLC2A5), solute carrier family 2 member 5;
HK2, hexokinase 2; GCK, glucokinase (hexokinase 4); KHK, ketohexokinase (fructokinase).
ND = Not detected.