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. 2011 Nov 11;6(11):e26994. doi: 10.1371/journal.pone.0026994

Figure 1. ET-1 transcription and histology in TET-1 lung.

Figure 1

(A) Bright-field micrographs of lung from NTg (1), 3771 TET-1 (2) demonstrated the tissue morphologies. In dark field micrographs of lung from NTg (3), 3771 TET-1 (4), ET-1 mRNA expression is represented as white silver grain. A  =  Alveoli; B  =  bronchiole; PA  =  pulmonary arteriole. Arrow in dark field shows ET-1 hybridization signal X 100 magnification. (B) Representative micrographs of tissues stained for collagen deposit (blue) by Masson Trichrome staining including lung alveoli (1–2), pulmonary arterioles and bronchioles (3–4) and heart (5–6). Qualitative observation indicated no obvious change in the sizes and structures of bronchioles, pulmonary arteries among TET-1 and NTg groups (B  =  bronchiole; PA  =  pulmonary arteriole and CA =  cardiac coronary artery) X 100 magnification, N = 5.