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. 2011 Nov 11;6(11):e26994. doi: 10.1371/journal.pone.0026994

Figure 2. Elevated blood pressure in TET-1 mice.

Figure 2

(A) Tail cuff measurement showed systolic blood pressure, mean blood pressure and diastolic blood pressure of 8-week-old TET-1 mice and NTg counterparts (N = 12). (B and C) Mean arterial blood pressure (MABP) was measured with polyethylene catheter in the right common carotid artery under anesthesia. (B) BQ-123 (1 mg/kg) and (C) BQ-788 (1 mg/kg) were injected intraperitoneally at the time indicated by the arrows. The hypertension in TET-1 mice from line 3771 (B) was inhibited by BQ-123 but not by BQ788 (C). Means±SEM (mmHg), *P<0.05, **P<0.01, #P<0.0001 when compared to vehicle control group of the same genotype, N = 3.