Table 1. Summary of the number of genes of each category characterized for each parameter examined.

	Viable	Lethal	Disease Viable	Disease Lethal	Disease Unknown	All Disease
Number of genes	672	1299	120	673	1172	1965
Number of genes with protein-protein interactions	489	1093	90	310	924	1324
Number of genes with gene ontology annotations	670	1288	119	670	1166	1955
Number of genes with disease class annotations	-	-	68	214	830	1112
Number of genes with disease mode of inheritance classifications	-	-	64	185	626	875
Number of genes with disease gain/loss of function classifications	-	-	73	219	987	1279

Data was not available for all genes for each parameter. Some analyses were performed only for disease gene datasets, such as disease classification, and others also evaluated for the viable and lethal datasets.