Table 1. Glomerular number, volume and sclerosis index. No parameters varied significantly between groups (WT =  wild type, Hetero  =  heterozygote, KO  =  knockout; n = 6 animals per group).

	Number of glomeruli (left kidney)	Mean glomerular volume [106 µm3]	Glomerular sclerosis index
femaleWT	22142±4318	0.54±0.19	0.75±0.69
maleWT	25004±6986	0.33±0.12	0.87±0.37
femaleHetero	21788±7458	0.37±0.17	1.31±0.33
maleHetero	20499±7988	0.50±0.25	0.98±0.46
femaleKO	22694±4454	0.35±0.11	0.98±0.13
maleKO	20278±4555	0.34±0.07	0.97±0.50
ANOVA	p = 0.798 (n.s.)	p = 0.113 (n.s.)	p = 0.433 (n.s.)