Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2011 Nov 11;6(11):e27478. doi: 10.1371/journal.pone.0027478

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Milkereit, Rotin.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

PMC Copyright notice

(A) ClustalW [49] amino acid sequence alignment of the LAPTM4 family members LAPTM4a (GenBank:AAH03158.1), 24 kDa-LAPTM4b (short) (GenBank: AAH31021.1), 35 kDa-LAPTM4b (long) (NP_060877.3) and LAPTM5 (GenBank: AAI06897.1). Putative transmembrane regions (predicted by SMART [50]) are highlighted in yellow, PY motifs are bold and underlined, and the UIM motif of LAPTM5 highlighted in blue. (B) PY motifs in the C-terminal tails of LAPTM4a and LAPTM4b are indicated in bold. Putative Tyrosine-based motifs are underlined. The dileucine motif is indicated in green (italicized), with the bold Leu shared with the PY motif. Tyrosine residues shared by tyrosine-based and PY motifs are indicated in red.