Fig. 5.

Functional connectivity reveals inverted somatomotor topography within the anterior lobe of the cerebellum that is comparable to task-evoked estimates. A: the cerebral (right hemisphere) and cerebellar (left hemisphere) locations of the hind paw (green), forepaw (red), and face (blue) somatomotor representations in the monkey are known from physiological responses to stimulation. Note that the representation of body space is inverted in the anterior lobe. [Adapted from Adrian (1943).] B: the cerebral somatomotor topography evoked by foot (green), hand (red), and tongue (blue) movements as measured by task fMRI in the human. C: the inverted somatomotor topography is clearly present in the anterior lobe of the contralateral cerebellum. D: right cerebral seed regions were defined based on the task activation data in B and reflected across the midline. The seed regions are illustrated for the right hemisphere to show their positions relative to the left hemisphere task data. E: the somatomotor map in the cerebellum is displayed based exclusively on functional connectivity MRI (fcMRI) with the contralateral cerebrum. The inverted somatomotor topography is present and similar to the task-based estimates, suggesting functional connectivity can resolve distinct regions of body space within the cerebellum. F: 3 views of somatomotor representation within the cerebellum are illustrated. Each estimate comes from a bilateral cerebral region and represents the extent of the functionally coupled response thresholded at r = 0.04. Displayed coordinates represent the plane in MNI atlas space. Note that the anterior lobe representation is inverted with the foot anterior to the hand and tongue, whereas the posterior lobe representation is upright with the tongue anterior to the hand and foot.