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The total content of collagen in the aorta was significantly decreased in hypertensive animals. The spices did not substantially correct this drop. Graph (left) with results from van Gieson staining, specimens stained with picrosirius red evaluated in polarized light (right). Con - control, L - L-NAME induced hypertension, P - piperine, C - curcumin. ** p < 0.01 versus Con, *** p < 0.001 versus Con.
