Table 1.
L | LP | LCP | LC | Con | P | CP | C | |
---|---|---|---|---|---|---|---|---|
PTAH | 26.38 ± 11.65* | 21.06 ± 10.52 + | 17.69 ± 5.02 ++ | 15.01 ± 8.52 +++ | 20.07 ± 7.12 | 21.58 ± 13.41 + | 17.45 ± 4.88 ++ | 21.50 ± 6.92 + |
actin | 18.87 ± 13.19*** | 24.81 ± 10.39*. + | 26.81 ± 8.41 ++ | 27.76 ± 8.50 +++ | 31.03 ± 9.00 | 32.69 ± 7.34 +++ | 30.48 ± 8.11 +++ | 27.96 ± 6.25 ++ |
elastin | 25.75 ± 3.93*** | 28.06 ± 3.92*** | 33.73 ± 3.09 +++ | 30.95 ± 8.36 + | 34.12 ± 7.88 | 33.26 ± 9.02 +++ | 33.78 ± 9.40 +++ | 34.74 ± 5.57 +++ |
collagen I | 12.48 ± 6.77** | 10.60 ± 8.23*** | 10.85 ± 3.45*** | 7.22 ± 4.76*** | 20.20 ± 12.10 | 22.67 ± 7.18 ++ | 18.67 ± 11.09 + | 22.11 ± 10.12 ++ |
collagen III | 0.23 ± 0.16* | 0.20 ± 0.17** | 0.30 ± 0.18* | 0.22 ± 0.24** | 0.50 ± 0.39 | 0.61 ± 0.44 + | 0.60 ± 0.51 ++ | 0.58 ± 0.43 ++ |
total collagen | 12.75 ± 6.89** | 10.81 ± 8.36*** | 11.15 ± 3.56*** | 7.44 ± 4.95*** | 20.71 ± 12.27 | 23.29 ± 7.41 +++ | 19.27 ± 11.46 +++ | 22.69 ± 10.38 +++ |
van Gieson | 15.14 ± 6.78*** | 17.45 ± 4.22*** | 17.35 ± 2.08*** | 13.98 ± 4.15*** | 25.57 ± 6.27 | 27.01 ± 5.42 +++ | 25.20 ± 3.34 +++ | 26.08 ± 3.82 +++ |
CSA | 0.77 ± 0.17* | 0.73 ± 0.19* | 0.62 ± 0.05 ++ | 0.73 ± 0.13* | 0.55 ± 0.04 | 0.54 ± 0.07 + | 0.55 ± 0.09 + | 0.55 ± 0.03 + |
thickness | 0.14 ± 0.03* | 0.14 ± 0.02** | 0.12 ± 0.01 | 0.14 ± 0.02*** | 0.11 ± 0.01 | 0.10 ± 0.01 ++ | 0.11 ± 0.01 + | 0.11 ± 0.01 + |
inner diameter | 1.42 ± 0.09 | 1.51 ± 0.15 | 1.43 ± 0.03 | 1.47 ± 0.12 | 1.54 ± 0.09 | 1.53 ± 0.12 | 1.58 ± 0.11 | 1.49 ± 0.13 |
The table summarizes the values of the relative content of various proteins in the media of the aorta expressed in% of the total cross sectional area (CSA), which is given in mm2, thickness and inner diameter in mm. Con - control, L - L-NAME induced hypertension, P - piperine, C - curcumin. + p < 0.05, ++ p < 0.01, +++ p < 0.001 versus L; * p < 0.05 versus Con, ** p < 0.01 versus Con, *** p < 0.001 versus Con.