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. 2011 Oct-Dec;28(4):147–158. doi: 10.4103/0970-9371.86339

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Copyright: © Journal of Cytology

This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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(a) Germinoma: Syncytial arrangement of loosely cohesive neoplastic cells with vacuolated cytoplasm, moderate nuclear pleomorphism, prominent nucleoli and frequent mitoses. Occasional interspersed mature lymphocytes are noted (H and E, × 200). (b) Medulloblastoma: Sheets of malignant cells with primitive appearing nuclei, attempted Homer-Wright rosettes and fine neuropil-like intercellular material (H and E, ×400). (c) GBM: Markedly pleomorphic malignant astrocytic cells in well-formed fibrillary meshwork (H and E, ×200). (d) GBM: Malignant small astrocytic cells in well-formed fibrillary meshwork with a hyperplastic blood vessel (H and E, ×100)