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. Author manuscript; available in PMC: 2011 Dec 1.
Published in final edited form as: Magn Reson Med. 2010 Oct 1;64(6):1542–1556. doi: 10.1002/mrm.22535

Figure 6.

Figure 6

Accuracy of voxel localization at 3T for Z-TOCSY-LASER (A), Z-TOCSY-STEAM (B), Z-TOCSY-PRESS (C), COSY-LASER (D), and L-COSY (E) sequences in a double layer phantom containing an outer shell of oil and an inner core of brain metabolites at physiologic concentrations (the voxel position is shown in F). A large lipid contamination signal (Lip) originating from outside the voxel is observed for semi-adiabatic (B,C) and non-adiabatic (E) sequences. Instead, in the case of fully adiabatic sequences (A,D) the lactate signal (Lac) originating from inside the voxel can be detected. All TOCSY experiments used the same mixing as detailed in Fig. 5. The LASER block used in A and D was the same as in Fig. 5. STEAM and PRESS used echo times of 20 ms and 30 ms, respectively. The L-COSY sequence used an echo time of 30 ms. The same repetition time (TR = 1.8 s) and number of averages (NA = 8) were used in all experiments.