Table 2.

Summary of experimental performance.

Sequence	Transfer efficiency (b)	Localization accuracy	SNR	SAR (%) (d)
Z-TOCSY-LASER	60%	++++	+++	100
Z-TOCSY-STEAM	60%	−	+++ (c)	72
Z-TOCSY-PRESS	60%	−	+++ (c)	72
TOCSY-LASER (a)	12%	++++	+	94
COSY-LASER	100%	++++	++++	28
L-COSY	100%	−	++++ (c)	7

^a)The sequence design from Ref. (29) was used;

^b)The efficiency calculated as percentage for the same mixing time of 64 ms (close to 1/2J = 72 ms for lactate) and the low-power condition γB_1,max = 0.76 kHz in the case of TOCSY;

^c)when the signal is adjusted to the size of the real voxel selected by the localization;

^d)SAR calculated and measured at 3T (transmit body RF coil) by the watchdog monitor in percentage from the maximum of 3W/kg allowed for the brain in a volunteer case when using the same TR = 2 s and 64 ms mixing time at the low power condition for TOCSY (for other organs with lower SAR limits shorter TR < 2s is possible with the most intense Z-TOCSY-LASER sequence, the semi-adiabatic sequences Z-TOCSY-STEAM and Z-TOCSY-PRESS can be run on brain with TR = 1.5 s). Plus (+) and minus (−) symbols are given as a qualitative measure for the performance (for localization minus indicates poor localization as proven by the presence of contaminating signal from lipids).