Table 1.

Binding motif of the SLA-1*0401 allele determined by PSCPL strategy

SLA-1*0401	Amino acid position in peptide
	1	2	3	4	5	6	7	8	9
A	1.7	0.8	1.6	1.1	0.8	0.4	1.7	0.7	0.0
C	0.8	0.2	0.4	2.7	1.1	1.0	0.7	1.7	0.0
D	0.4	0.7	7.7	2.1	0.8	0.1	0.5	1.8	0.0
E	1.6	0.0	2.8	0.6	1.0	1.4	0.9	0.9	0.2
F	0.4	0.2	0.8	0.0	1.0	1.1	1.1	1.1	5.8
G	0.5	0.3	0.1	1.5	1.1	1.4	0.0	1.0	0.0
H	0.5	0.2	0.1	0.1	1.3	2.4	0.5	0.7	0.4
I	0.7	3.4	0.3	0.8	0.8	0.9	0.7	0.9	0.3
K	1.1	0.2	0.1	0.4	0.4	1.2	0.4	0.9	0.0
L	0.6	2.1	0.2	0.6	1.0	1.7	1.0	1.2	0.6
M	1.7	1.9	1.0	1.2	1.4	1.4	1.2	1.4	0.7
N	1.4	0.5	0.6	1.4	1.9	0.7	1.0	1.9	0.0
P	0.0	0.0	0.1	1.6	0.5	1.1	1.9	1.2	1.1
Q	1.0	0.9	0.2	1.0	0.5	0.4	0.8	0.7	0.0
R	2.3	0.0	0.1	0.6	2.4	0.9	1.0	0.5	0.2
S	1.8	2.4	1.8	1.1	0.8	1.5	1.6	0.7	0.0
T	1.4	2.5	1.6	0.7	0.9	0.5	2.0	0.7	0.0
V	1.1	3.7	0.3	0.5	0.7	0.8	0.9	0.6	0.8
W	0.3	0.0	0.2	0.6	1.0	0.8	0.6	1.4	5.6
Y	0.6	0.0	0.5	1.3	0.6	0.2	1.6	0.3	4.3
Sum	20	20	20	20	20	20	20	20	20
AP value	7	28	57	8	4	6	5	4	67

The normalized relative binding (RB) value indicates whether an amino acid is favored (RB > 2, bold numbers) or disfavored (RB < 0.5, italic numbers) in a given peptide position. The anchor position (AP) value is given by the equation ∑(RB − 1)². The important anchor positions 2, 3, and 9 for SLA-1*0401 are underlined