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. 2011 Jul 8;63(12):821–834. doi: 10.1007/s00251-011-0555-3

Table 2.

Comparison of PSCPL derived binding motifs for the three MHC-I heavy chains HPP, PHP, and PPP (hα123, pα123, and SLA-I*0401) regarding peptide positions 2 and 9

Molecule: HPP Position in peptide Molecule: PPP Position in peptide Molecule: PHP Position in peptide
Amino acid 2 9 Amino acid 2 9 Amino acid 2 9
A 0.3 0.4 A 0.8 0.0 A 1.0 0.0
C 0.2 0.4 C 0.2 0.0 C 0.0 0.0
D 0.2 0.4 D 0.7 0.0 D 0.0 0.0
E 0.2 0.4 E 0.0 0.2 E 0.0 0.0
F 0.0 0.4 F 0.2 5.8 F 0.1 0.5
G 0.2 0.4 G 0.3 0.0 G 0.4 0.0
H 0.2 0.4 H 0.2 0.4 H 0.2 0.5
I 2.4 0.4 I 3.4 0.3 I 2.7 0.1
K 0.2 2.3 K 0.2 0.0 K 0.1 0.0
L 0.0 0.4 L 2.1 0.6 L 1.8 0.4
M 5.3 0.4 M 1.9 0.7 M 2.1 0.7
N 0.0 0.4 N 0.5 0.0 N 0.2 0.0
P 0.2 0.4 P 0.0 1.1 P 0.0 0.7
Q 0.0 0.4 Q 0.9 0.0 Q 1.1 0.0
R 0.2 9.6 R 0.0 0.2 R 0.2 0.0
S 3.4 0.4 S 2.4 0.0 S 2.8 0.0
T 4.8 0.4 T 2.5 0.0 T 3.6 0.0
V 1.6 0.4 V 3.7 0.8 V 3.3 0.3
W 0.2 0.4 W 0.0 5.6 W 0.1 0.2
Y 0.2 0.4 Y 0.0 4.3 Y 0.2 16.5
Sum 20 20 Sum 20 20 Sum 20 20
AP value 51 81 AP value 28 67 AP value 30 254

RB and AP values are defined as described in Table 1