Table 3.
Local Maxima for Significant Within- and Between-Group Activations
| Region (Contrast) | z Score | x, y, and z Coordinatesa | ||
|---|---|---|---|---|
| Between groups: before to after treatment (bupropion > placebo) | ||||
| Ventral striatum, left | 4.10 | -14, | 14, | -10 |
| 3.65 | -12, | 6, | -12 | |
| Medial orbitofrontal cortex, left | 3.58 | 6, | 46, | -10 |
| Anterior cingulate cortex, bilateral | 3.48 | 0, | 36, | -4 |
| Within bupropion: before to after treatment (pretreatment > posttreatment) | ||||
| Precuneus, bilateral | 3.80 | 2, | -68, | 56 |
| 3.42 | 0, | -76, | 44 | |
| 3.04 | -2, | -64, | 48 | |
| Lateral occipital cortex, bilateral | 3.25 | -12, | -80, | 50 |
| 3.12 | 48, | -74, | 24 | |
| 2.98 | 40, | -78, | 34 | |
| Anterior cingulate cortex, bilateral | 2.91 | 8, | 40, | -8 |
| 2.88 | 2, | 40, | 10 | |
| 2.83 | -4, | 40, | 22 | |
| Between groups: after treatment (placebo > bupropion) | ||||
| Anterior cingulate cortex, left | 3.90 | -4, | 34, | 0 |
| Ventral striatum, left | 3.67 | -18, | 14, | -10 |
| 3.59 | -14, | 14, | -10 | |
| 3.56 | -10, | 14, | -8 | |
a
Coordinates in MNI152 standard space; x, y, and z refer to right/left (x: positive = right), anterior/posterior (y: positive = anterior), and dorsal/ventral (y: positive = dorsal).